Hubungan Quick Of Blood (QB) Dan Urea Reduction Ratio (URR) Dengan Pruritus Uremik Pada Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisis Di Ruang Hemodialisis Rsud Sultan Imanuddin Pangkalan Bun

Abstract

Background: Uremic pruritus remains a frequent and distressing complication among hemodialysis patients, often attributed to insufficient solute clearance. Quick of Blood (QB) and Urea Reduction Ratio (URR) serve as critical parameters for evaluating dialysis adequacy and may be associated with pruritus severity.  Objective: This study aims to analyze the relationship between QB and URR with the occurrence of uremic pruritus in patients undergoing maintenance hemodialysis.

Methods: A descriptive correlational study with a cross-sectional design was conducted on 52 patients, selected via purposive sampling. Pruritus severity was assessed using the Numerical Rating Scale (NRS). Spearman’s rank correlation test was employed for statistical analysis.

Results: The majority of patients had moderate QB levels (71.2%) and inadequate URR (82.7%), with most reporting moderate pruritus (38.5%). A statistically significant correlation was found between QB and pruritus (p = 0.001; r = 0.459), as well as between URR and pruritus (p = 0.001; r = 0.629).

Conclusion: Reduced QB and suboptimal URR are associated with increased severity of uremic pruritus. Ensuring adequate dialysis delivery by adjusting QB according to patient characteristics and achieving optimal URR is essential to mitigate pruritus and improve patient outcomes.